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Silver Bullet Therapeutics, Inc., a privately held company located in San Jose, Calif., has developed and patented antimicrobial coating processes as well as implants and medical devices to address surgical-site infections (SSIs) and hospital-acquired infections (HAIs). The company’s first commercial product, the OrthoFuzIon Bone Screw System, utilizes an advanced silver ion technology that allows for rapid and sustained ionization of the silver and creation of an antimicrobial zone around the screw to prevent microbial colonization of the implanted devices. OrthoFuzIon is a Trademark of Silver Bullet Therapeutics, Inc., and is currently approved for sale only in the European Union.

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